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These studies demonstrate that increased extracellular adenosine through AK inhibition can elicit modulatory effects on EEG slow waves via an interaction with central ADO receptor subtypes. ABT 702 Dihydrochloride Solid powder Inhibitors ABT 702 Dihydrochloride is a potent non-nucleoside adenosine kinase inhibitor, selective over other sites of adenosine interaction like A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase. ABT-702 dihydrochloride - 10 mm/1 ml - HY-103161-1mL from MedChem Express ABT-702. Compare Products ; Buying Guide; Scientific Support; Distributors; About Us; Contact Us; Skip to Content. Toggle Nav. My Cart Checkout +44 (0)1223 859 353 ABT 702 Dihydrochloride is a potent non-nucleoside adenosine kinase inhibitor, selective over other sites of adenosine interaction like A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase.
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ABT-702 dihydrochloride: CAS Number: 1188890-28-9: 1.2 Relevant identified uses of the substance or mixture and uses advised against; Identified uses: For research use only, not for human or veterinary use. 1.3 Details of the supplier of the safety data sheet; Company: Abmole Bioscience Inc. 8300 FM 1960 West, Suite 450 Houston, TX 77070, USA Similarly ABT‐702 tended to produce greater effects after carrageenan inflammation, however this did not reach significance. Protection of endogenous adenosine by ABT‐702 therefore produces a marked inhibition of the noxious evoked neuronal activity in inflamed and neuropathic rats. ABT-702 increases extracellular adenosine levels in the isolated spinal cord of neonatal rats (Takahashi et al., 2010). Accordingly, ABT-702 may affect neuronal activities of nociceptive pathways in the spinal cord.
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702. 259 NJA 2007 s. Sterco följer stadgar, regler och rekommendationer i AB 04 samt ABT 06 i de uppdrag AB 04 och ABT 06 kan tillhandahållas här. A@sterco.se 08 47 47 702. av L Karlsson · 2017 — ABT. Allmänna bestämmelser för totalentreprenader avseende byggnads-, skadeståndsansvar för vilseledande information, JT. 1994/95, s. 702-716 Verkstadsgatan 2, 702 27 Örebro, Tel: +46 (0)19-23 70 30. Copyright © Maptun Performance AB Integritetspolicy · SAAB Original Facebook Google+ Youtube.
ABT-702 dihydrochloride: CAS Number: 1188890-28-9: 1.2 Relevant identified uses of the substance or mixture and uses advised against; Identified uses: For research use only, not for human or veterinary use. 1.3 Details of the supplier of the safety data sheet; Company: Abmole Bioscience Inc. 8300 FM 1960 West, Suite 450 Houston, TX 77070, USA
Similarly ABT‐702 tended to produce greater effects after carrageenan inflammation, however this did not reach significance. Protection of endogenous adenosine by ABT‐702 therefore produces a marked inhibition of the noxious evoked neuronal activity in inflamed and neuropathic rats.
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ABT 702 was also highly selective for AK inhibition as compared to other sites of ADO action including ADA, ADO receptors, and ADO transport sites [1]. In vivo: ABT 702 had dose-dependent antinociceptive and antiinflammatory actions in a variety of animal models of nociceptive, inflammatory, and neuropathic pain. 3 ABT-702 produced inhibition of the postdischarge, wind-up and C-fibre evoked responses in both carrageenan and nerve-injured animals.
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It displays oral activity in animal models of pain and inflammation.